Symbol Name ID |
Gata3
GATA binding protein 3 MGI:95663 |
Darker colors indicate more annotations |
Human Phenotypes | Abnormality of T cell physiology |
Psoriasiform dermatitis |
Disease(s) Associated with GATA3 | ||
hypoparathyroidism-deafness-renal disease syndrome |
Mouse Phenotypes | increased T cell apoptosis |
small thymus |
decreased thymocyte number |
abnormal T cell differentiation |
decreased double-negative T cell number |
abnormal double-positive T cell morphology |
decreased double-positive T cell number |
arrested T cell differentiation |
decreased eosinophil cell number |
abnormal T cell subpopulation ratio |
abnormal T cell number |
increased T-helper 1 cell number |
decreased T-helper 2 cell number |
decreased CD4-positive, alpha-beta T cell number |
abnormal CD8-positive, alpha-beta T cell number |
decreased gamma-delta T cell number |
decreased T cell number |
abnormal CD4-positive, alpha beta T cell morphology |
decreased IgE level |
abnormal immune system cell morphology |
abnormal immune system organ morphology |
abnormal humoral immune response |
increased interferon-gamma secretion |
decreased interleukin-13 secretion |
decreased interleukin-4 secretion |
increased susceptibility to parasitic infection |
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Availability | Mouse Genotype | ||||||||||||||||||||||||||
Gata3tm1Jeng/Gata3tm1Jeng | |||||||||||||||||||||||||||
Gata3tm1Jml/Gata3tm1Jml | |||||||||||||||||||||||||||
Gata3tm2Jeng/Gata3tm2Jeng | |||||||||||||||||||||||||||
Gata3tm1.1Mbu/Gata3tm1.1Mbu (conditional) | |||||||||||||||||||||||||||
Gata3tm1Iho/Gata3tm1Iho Tg(Lck-cre)1Cwi/0 (conditional) |
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Gata3tm1Iho/Gata3tm1Iho Tg(Cd4-cre)1Cwi/0 (conditional) |
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Gata3tm1Iho/Gata3tm1Iho Il13tm1(YFP/cre)Lky/Il13+ (conditional) |
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Gata3tm1Jfz/Gata3tm1Jfz Tg(Cd4-cre)1Cwi/0 (conditional) |
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Gata3tm1Jfz/Gata3tm1Jfz Tg(Tnfrsf4-cre)1Nik/0 (conditional) |
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Gata3tm3Gsv/Gata3tm3Gsv Tg(KRT14-cre)8Brn/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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